Klinefelter syndrome, also called testicular dysgenesis, is the phenotype of the 47,XXY genotype and is characterized by male hypogonadism and infertility. Klinefelter Syndrome is probably the most common chromosomal variation found in humans. In random surveys, it is found to appear about once in every 500 to one in every 1,000 live born males. Since the largest percentage of these men would have never been diagnosed otherwise, it shows that in many cases affected individuals lead healthy, normal lives with no particular medical or social questions. Klinefelter Syndrome is diagnosed through a karyotype; a chromosome analysis usually done on a blood sample. Klinefelter Syndrome is caused by a chromosome variation involving the sex chromosomes. The person with Klinefelter Syndrome is a male who, ....

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