Scientists have finally found out why MPA medroxyprogesterone, otherwise known as Provera performs just as well in low doses in small children who are dealing with early sex traits, as it does for women in high doses with breast cancer. You may have heard of Provera before as the drug that delivers hormone replacement therapy for women who are going through menopause. Two scientists, named Lee and Auchus were trying to figure out why Provera is able to treat both early puberty as well as breast cancer. During the pre-teen years a chemical is released in the brain called gonadotropin-releasing hormone (GnRH). In a normal pre-teen body GnRH tells the ovaries and testes when to start making steroids. Low doses of Provera have shown to bind to the receptors in the brain and block GnRH production. There are certain disorders that children can develop- when their GnRH is not released into the b....

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Number Of Words: 377

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