The Fabry Disease The Fabry Disease is a hereditary disorder, caused by the lack of alphagalactosidase A. It is an x-linked recessive inheritance. Therefore it is the females that carry it. The ones who are mostly affected by this disease are the males. Female carriers, though, may develop angiokeratomas and may have problems with burning pains. Very few of the carriers may also have kidney or heart problems. This disease occurs in 1 of 40,000 people. Descriptions A person with the Fabry disease develops angiokeratomas, which are clusters of raised, dot-like lesions. Appearing during childhood or puberty in the genital and thigh areas, these angiokeratomas increase in size and number. Other symptoms of this disease are burning pains in hand or feet, nausea, vomiting, abdominal pains, dizziness, headaches and generalized weakness. Swelling of the legs, caused by the gather....

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