Lime Disease Lyme disease is caused by Borrelia burgdorferi, which is a tick-borne spirochete. The dangers of this disease became more publicised in 1977, where a geographic grouping of children in Lyme, Conneticut were thought to have juvenile rheumatoid arthritis1. Soon after, it was discovered that lyme disease was an illness that mainly affects the skin, nervous system, heart, and joints. The borrelia species is part of the eubacterial phylum of spirochetes. Containted within a protoplasmic cylinder is a cell membrane, followed by wavy flagella, and then an outer membrane. The genes encoded within the outer membrane are located on