Hemophilia Manitoba Hemophilia Manitoba, or hemophilia, is a sex-linked genetic disorder that is effecting about 20,000 Americans, most of which males. A person with hemophilia either has an inactive or inadequate supply of one of several blood factors needed for blood to clot. Because of this hemophilia can be mild, moderate, or severe. Severe hemophiliacs are at risk for bleeding during surgery, trauma, or even dental work. There are two types of hemophilia, A and B (Christmas disease). Hemophilia B is extremely rare. The majority of the people have hemophilia A. In hemophilia A, the particular f