Bacterial Resistance Bacterial resistance is a problem that has profoundly impacted the medical community. Bacterial resistance results when bacteria become resistant to individual antibiotics through the development of specific defense mechanisms which render the antibiotic ineffective. This problem has become evident in recent years as numerous cases have been reported in which antibiotics are not effective against the bacteria that they have fought off for years. The recent troubles with bacterial resistance have caused panic throughout the United States. The pharmaceutical industry hasn’t