Diabetes Mellitus is a disorder in which blood levels of glucose are abnormally high because the body doesn’t release or use insulin adequately. Diabetes Mellitus affects many organs of the body. It affects the blood vessels because Atherosclerotic plaque builds up and blocks large or medium-sized arteries in the heart, brain, and legs. The walls of small blood vessels are damaged so that the vessels do not transfer oxygen normally and may leak. This can lead to poor circulation and can hinder the healing of wounds, cause heart disease, stroke, gangrene of the feet and hands, and infections. The eyes are also affected. The small blood vessels of the retina become damaged lead