In Shakespeare’s Macbeth, Macbeth and Lady Macbeth both show signs of what would today be diagnosed as symptoms of schizophrenia. Schizophrenia is defined as "a psychotic disorder characterized by loss of contact with the environment, by noticeable deterioration in the level of functioning in everyday life, and by disintegration of personality expressed as disorder of feeling, thought, and conduct." There are three major symptoms of the disorder; not being able to distinguish the difference between fantasy and reality, incoherent conversations, and withdrawal physically and emotionally. The most common and most well known symptom