Biography of Christopher Columbus Columbus, Christopher (Italian Cristoforo Colombo, Spanish Cristóbal Coló n) (1451-1506), Italian-Spanish navigator who sailed west across the Atlantic Ocean in search of a route to Asia but achieved fame by making landfall, instead, in the Caribbean Sea. Columbus was born in Genoa, Italy. His father was a weaver, and it is believed that Christopher entered this trade as a young man. Information about the beginning of his seafaring career is uncertain, but the independent city-state of Genoa had a busy port, and he may have sailed as a commercial agent in his youth. In